Without drug With new drug 1.8 3 2 3.6 3.4 4 3.5 4.4 3.7 4.5 3.8 5.2 3.9 5.5 3.9 5.7 4 6.2 4.9 6.3 5.1 6.6 5.2 7.8 5 7.2 4.5 6.5 4.2 5.6 4.7 5.9